Doris Packer was born Doris Edwards in Menominee in Menominee County in the Upper Peninsula of Michigan. Her family moved to southern California when she was quite young. She became interested in acting while in high school. After attending the University of California at Los Angeles, she moved to New York City to study under noted drama teacher Evelyn Thomas. Packer also appeared in Broadway shows. During World War II, Packer enlisted in the U.S. Army Women’s Army Corps (WACs), joining in 1943 as a Private and eventually reaching the rank of Technical Sergeant. Her discharge records were likely lost in the 1973 fire at the National Personnel Records Center. In 1954, she appeared as Florence on an episode (“Sixteen Vertical”) of Rod Cameron’s crime drama series, City Detective. In 1955-1956, Packer appeared three times as a nurse in the NBC sitcom It’s a Great Life, featuring Frances Bavier. In 1958, she guest-starred on Rod Cameron’s subsequent syndicated series, State Trooper, in “The Last Stage Robbery”, an episode with a surprise ending.

Packer played wealthy society matrons on The George Burns and Gracie Allen Show and I Love Lucy and as Mrs. Wiley on The Andy Griffith Show. She had a recurring role as Clara Mason in the 1960-1961 NBC trivial sitcom Happy, set at a Palm Springs motel and featuring a talking baby. Her co-stars included Ronnie Burns, Yvonne Lime Fedderson, and Lloyd Corrigan. Packer played Mrs. McGillicuddy in the 1961 episode “Gladys’ Political Campaign” on the CBS sitcom, Pete and Gladys, with Harry Morgan and Cara Williams. She played the wealthy Mrs Huntingdon in a 1963 episode “I’m No Henry Walden!” on CBS’s The Dick Van Dyke Show. She appeared on three episodes of The Beverly Hillbillies as wealthy matron Mrs. Fenwick. She made a guest appearance on Perry Mason in 1962 as Mrs. Campion in “The Case of the Polka Dot Pony.” Packer appeared on NBC’s anthology series, The Barbara Stanwyck Show. In 1964–1965, Packer appeared on the short-lived CBS sitcom, Many Happy Returns, starring John McGiver and set in the complaint division of a fictitious Los Angeles department store with the unlikely name of Crockmyer’s. In 1973, she guest-starred in an episode of the situation comedy A Touch of Grace. Packer was married to stage director Rowland G. Edwards for twenty-five years — from 1928 until his death in 1953; they had no children. She died at the age of seventy-four in 1979 in Glendale, California, from natural causes.