Domino Harvey dropped out of school as a teenager to pursue a career in modeling, but did not enjoy working in the industry. Harvey later claimed to have attended the Lee Strasberg Institute and been represented by the Ford Modeling Agency; in a 2005 article, Aida Edemariam of The Guardian notes that she was unable to verify these claims independently. She studied sound engineering and subsequently worked as a DJ at several clubs in London, managing one of them. Around that time, she lived in Notting Hill and also designed and sold T-shirts at Kensington Market, London. At age 19, after spending time in Israel, Harvey moved to Southern California, where her mother had relocated years earlier after marrying the American businessman Peter Morton. Harvey had previously resisted the idea of moving to the United States. In California, Domino Harvey initially worked as a DJ at clubs in Los Angeles. She then worked on a ranch near San Diego, and served as a volunteer firefighter in Boulevard, California. At that time, her friends trained her in the use of firearms. After serving as a volunteer firefighter for a year, Harvey trained as an EMT and took courses in fire science. In 1993, she unsuccessfully applied to the Los Angeles Fire Department, and then enrolled in a short course to become a bail recovery agent, or bounty hunter.

After completing a bail recovery agent training course, Domino Harvey began working with the teacher of the course, Ed Martinez, at a bail bond agency in South Los Angeles run by Celes King III. Very few women work in the bounty hunting industry. As a bounty hunter, she primarily sought drug dealers and thieves, but occasionally tracked murderers. She enjoyed the work and Martinez later stated that she was one of the most skilled bounty hunters he knew. She primarily worked with two other bounty hunters when tracking fugitives. During their operations, she occasionally posed as a lost tourist. Harvey collected swords and knives, and kept AK-47s in her apartment. As a bounty hunter in the mid-1990s, Harvey earned roughly $30,000–40,000 annually. The agency where Harvey worked was paid 10% of the bail posted by each fugitive that they caught. She said that she chose bounty hunting for the excitement of the work, even though it was not a high-paying job. She typically worked in Southern California, but on one occasion traveled across the United States to Atlanta, Georgia, to seek one of the FBI Ten Most Wanted Fugitives.

Domino Harvey lived above the garage of her mother’s home in Beverly Hills. After she began working as a bounty hunter, the British Daily Mail newspaper published an article about her. Director Tony Scott read the article and contacted Harvey. They soon became friends and regularly visited each other; Scott spent time observing her while she tracked fugitives. Their friendship lasted for the rest of her life. Harvey entered drug rehabilitation clinics four times; each stay was funded by her mother. Scott claims that Harvey and the bounty hunters with whom she worked would often keep drugs that they found when arresting criminals. Martinez has stated that they used marijuana, cocaine, and heroin. In 1997, Harvey traveled to a drug rehabilitation clinic in Hawaii. She lived in Hawaii for two years. In 2001, having returned to California, she attempted to become a bounty hunter again but was unable to find work with her previous employer.

In 2003, Domino Harvey was arrested on charges of possession of crystal methamphetamine after sheriff’s deputies found the drug at her home while investigating a burglar alarm call-out. She pleaded guilty to drug possession charges and attended a treatment program; the arrest was consequently removed from her criminal record. In May 2005, Harvey was arrested on federal charges of trafficking methamphetamine; she maintained that she was innocent. She spent three weeks in a Metropolitan Detention Center in Los Angeles. She posted $1 million bail and was placed under house arrest, staying at her home in West Hollywood. While under house arrest, Harvey wore an electronic monitoring ankle bracelet. Harvey continually denied that she was a drug trafficker, claiming to have been set up. While under house arrest, she lived with a person whom she had hired as a “sober guardian” to help her refrain from drug use. On the night of June 27, 2005 her aide discovered her unconscious in her bathtub. She was taken to a hospital but could not be resuscitated. The Los Angeles County Coroner’s office determined that she had overdosed on the painkiller drug fentanyl.