Andy Clyde’s last theatrical film was released in 1956, after which he worked mostly in television, having appeared on Rod Cameron’s syndicated series City Detective. On The Pepsi-Cola Playhouse and Studio 57 in 1954 and 1955, respectively, he portrayed Tom Harper in the episode “Santa’s Old Suit,” with co-star Jane Darwell. Clyde guest starred in several other early series too, including The People’s Choice, Soldiers of Fortune, My Little Margie, The Bob Cummings Show, and Lock Up. He appeared in two children’s programs: as Colonel Jack in four episodes of Circus Boy and as Homer Tubbs in four segments of ABC’s western series, The Adventures of Rin Tin Tin. In 1959, Clyde played Captain Gibbs in two segments of the ABC/Warner Brothers western series, Colt .45. As “Scatterbrain Gibbs”, he appeared with Tol Avery as Barnes in “Queen of Dixie”; in the story line, series character Christopher Colt (Wayde Preston) is aboard a Mississippi River gambling boat and encounters a ring of counterfeiters. Clyde subsequently played “Captain Gibbs” in the episode “Yellow Terror”, with Brad Dexter in the role of John Barker. That same year, Andy Clyde portrayed millionaire “Andrew C. Cooley” in CBS’s fantasy drama, The Millionaire. Andy Clyde and Denver Pyle were cast in the 1960 episode “The Man Who Wanted Everything” of the ABC western drama, The Man from Blackhawk, starring Robert Rockwell as a roving insurance investigator.

From 1960 to 1962, Andy Clyde was cast as the farmer Pa McBeam in five episodes of NBC’s western series, The Tall Man, starring Barry Sullivan and Clu Gulager. Judy Nugent plays McBean’s daughter, June. In three episodes, Olive Sturgess played daughter May McBeam. In “The Reluctant Bridegroom” (February 18, 1961), Ellen Corby is featured as Hannah Blossom, a potential mail order bride, for Pa McBeam. Through a fraudulent letter written by the McBeam daughters, Hannah is lured to Lincoln, New Mexico, the setting of the series, to seek out the potential husband. In “Substitute Sheriff” (January 6, 1962), the McBeam daughters enlist their father as an acting sheriff in a scheme to thwart the seizure of their property for right-of-way by the railroad. Bob Hastings appears in this episode as J. S. Chase. In 1962–1963, Clyde portrayed Dr. Parkinson in three episodes of NBC’s medical drama, Dr. Kildare, starring Richard Chamberlain. Clyde was featured several times on Rory Calhoun’s CBS western series, The Texan, including the part of Wild Jack Hastings in “The Troubled Town” and in additional segments as the character Andy Miles. Andy Clyde further guest starred in such westerns as Wagon Train, Tales of the Texas Rangers, The Restless Gun, Jefferson Drum, Buckskin, Fury, Shotgun Slade, The Man from Blackhawk, and The Life and Legend of Wyatt Earp (as Billy Buckett).

On Lassie, Andy Clyde played the eccentric farmer and nature lover, Cully Wilson, the friend to Timmy Martin, portrayed by child actor Jon Provost, in much the same fashion as Burt Mustin was cast as Gus the fireman for Jerry Mathers in Leave It to Beaver. In The Real McCoys, Clyde performed as the foil for another veteran character actor, Walter Brennan. Clyde played friendly, usually sincere neighbor George MacMichael to Brennan’s devious “Grandpa Amos McCoy.” Madge Blake played Flora, the sister of George McMichael with something of a romantic interest in Amos McCoy. Later, Clyde was cast as Skippy Draper in one episode of another Brennan ABC series, The Tycoon. In 1961, on CBS’s The Andy Griffith Show, Clyde played Frank Myers, an eccentric old man whom the town tries to evict in the episode “Mayberry Goes Bankrupt.” Clyde portrayed Poney Thompson in “Snakebite” in 1958 and Henry Squires in “Durham Bull” in 1962 on CBS’s long-running Gunsmoke. Clyde appeared as Grandpa Jim Anderson in five episodes of the 1964-1965 ABC military comedy, No Time for Sergeants, starring Sammy Jackson. The series was inspired by an earlier Andy Griffith film of the same name. Andy Clyde continued to perform on television until his death. His remains were interred at Forest Lawn Memorial Park in Glendale, California.