Doris Kenyon grew up in Syracuse, New York, where her family had a home at 1805 Harrison Street. Her father, Dr. James B. Kenyon, was a Methodist Episcopal Church minister at University Church. Kenyon studied at Packer College Institute and later at Columbia University. She sang in the choirs of Grace Presbyterian and Bushwick Methodist Churches in Brooklyn, New York. Her voice attracted the attention of Broadway theatrical scouts who enticed her to become a performer on the stage. She first appeared in the Victor Herbert operetta The Princess Pat. In 1915 she made her first film, The Rack, with World Film Company of Fort Lee, New Jersey. One of the most remembered films of her early career is Monsieur Beaucaire (1924). In this production she starred opposite Rudolph Valentino. She was with Paramount Pictures for the studio’s first dramatic, all-talking film, Interference, in 1928. Kenyon was cast opposite actor George Arliss in two films. These are Alexander Hamilton (1931) and Voltaire (1933). She participated in Counsellor at Law (1933) with John Barrymore. In the autumn of 1935 Doris appeared with Ramon Navarro in the play, A Royal Miscarriage, in London, England. Kenyon’s film career ended with a cameo in The Man in the Iron Mask (1939). Kenyon played Ann Cooper in the soap opera Crossroads on NBC in the 1940s.

Kenyon continued her acting career in television in the 1950s. She was cast in episodes of The Secret Storm (1954), Schlitz Playhouse of Stars and 77 Sunset Strip. Kenyon was married a number of times. Her first husband was the actor Milton Sills. She wed Sills in 1926. She was widowed in 1930. She had one son with Sills named Kenyon. She married prosperous New York real estate broker, Arthur Hopkins, in 1933. The two divorced the following year, citing incompatibility. In 1938 Doris married Albert D. Lasker, owner of Lord & Thomas, a prosperous advertising agency. They divorced in 1939. Her final marriage was to Bronislaw Mlynarski. He was the son of composer Emil Młynarski and the brother-in-law of Arthur Rubenstein. Doris Kenyon died in 1979 at her Beverly Hills home, of cardiac arrest, four days before her 82nd birthday.